Endocrine Abstracts

Objective: To describe the evolution of neurobehavioral and cognitive symptoms in patients with primary hyperparathyroidism as measured by mini-mental state (MMS), Hamilton’s anxiety and depression scale (HADS) and Clock tests. Scores were also compared with biochemical data.Methods: The Swiss primary hyperparathyroidism (PHPT) Cohort Study is an ongoing, prospective, non-interventional national project collecting clinical, biochemical and outcome d...

Objective: Evaluate cinacalcet use and effect based on follow-up within a cohort study of recently diagnosed Primary Hyperparathyroidism (PHPT) patients. Characteristics, treatment indications and biochemical data are presented with measures of cinacalcet efficacy and safety.Methods: The Swiss Primary Hyperparathyroidism Cohort Study is a prospective, non-interventional project to collect clinical, biochemical and outcome data in patients with PHPT initi...

Introduction: Amiodarone-induced thyrotoxicosis (AIT) is a well-known complication of amiodarone therapy. Type 1 AIT is caused by excessive iodine-induced thyroid hormone synthesis in abnormal thyroid glands and treated with thionamides; type 2 AIT is a drug induced destructive thyroiditis that responds to glucocorticoids. Mixed forms of AIT need a combined treatment of thionamides and glucocorticoids. In refractory cases of AIT plasmapheresis before total thyroidectomy is an ...